Home Cellular health Diabetes Dementia Harvard Connection Doctor Explain Active Lifestyle Cognitive Skills Aging Longevity Amyloid Plaque Hypertension Insulin Resistance Blood Glucose Hyper hypo

Diabetes Dementia Harvard Connection Doctor Explain Active Lifestyle Cognitive Skills Aging Longevity Amyloid Plaque Hypertension Insulin Resistance Blood Glucose Hyper hypo


Dementia Can Make Aging A Painful Process for People With Dementia | Photo credit: iStock images


  • Type 2 diabetes is largely a lifestyle-related disease caused by sedentary lifestyles and poor diet.
  • The WHO said in 2016 that more than 1.9 billion adults aged 18 and over were overweight. Among them, more than 650 million adults were obese.
  • Obesity harms overall health, and researchers now realize that fat itself can play a major role in regulating cognitive health.

According to Global Burden of Disease Study, 4.7 million people died prematurely in 2017 from obesity. To put this in context: it was almost four times the number of deaths in road crashes and almost five times the number of deaths from HIV / AIDS in 2017.

Due to increasing rates of obesity, inactivity and an aging population, type 2 diabetes is more prevalent in our society than ever before. A harvard report says that the fact that type 2 diabetes is now frequently seen in children, due to their obesity and inactivity – is a worrying reality.

Type 2 diabetes has been known for many years to increase the risk of stroke and heart disease. More recent studies have shown that diabetes also increases your risk for dementia – writes Dr. Andrew E Budson, head of cognitive and behavioral neurology at the Veterans Affairs Boston Healthcare System. Dr Budson is Senior Lecturer in Neurology at Harvard Medical School and Chairman of the Science of Learning Innovation Group at Harvard Medical School Academy.

He says what hasn’t been studied before, however, is whether the age of onset of diabetes makes a difference in your risk of developing dementia.

Dementia is a disease of old age, usually characterized by a gradual decline in cognitive functions from the previous level. Memory loss for recent events is a classic feature. It affects a number of cognitive functions, including new learning, intelligence, decision making, executive functioning, and language.

New research on age of diabetes onset and risk of developing dementia

  1. A recently published study examined the association between the age of onset of diabetes and the development of dementia using a large, ongoing cohort study that was established in 1985-1988 with 10,308 employees. aged 35 to 55 in London-based ministries.
  2. From 1985 to 2019, 1,710 cases of diabetes and 639 cases of dementia were recorded. For 1,000 people examined each year, the rates of dementia were 8.9 in people without diabetes by the age of 70.
  3. Comparable rates of dementia among diabetics were 10.0 for those who started up to five years earlier, 13.0 for six to 10 years earlier, and 18.3 for more than 10 years earlier.
  4. These striking results clearly show that the earlier you develop diabetes, the greater your risk of developing dementia.

How diabetes can lead to dementia:

  • Dr Budson writes: “There are many reasons why years of type 2 diabetes can lead to dementia. One of the reasons has to do with the effects of diabetes on the heart, as heart health is linked to brain health. Heart disease and high blood pressure are both associated with stroke which, in turn, can lead to dementia. However, strokes don’t seem to be the complete answer, as some studies have shown that diabetes leads to an increased risk of dementia even when strokes are under control. “
  • Another factor is the episodes of hypoglycemia that commonly occur in diabetes. While tight blood sugar control has been shown to reduce long-term risk of heart disease and stroke, tight control can also lead to hypoglycemia, memory loss, and dementia. The reason here is probably due to the fact that hypoglycemia is known to damage the hippocampus, the memory center of the brain.

Does Diabetes Directly Cause Alzheimer’s Disease?

  1. Alzheimer’s disease has even been called “type 3 diabetes” because of the molecular and cellular characteristics shared between diabetes and Alzheimer’s disease.
  2. Insulin plays an essential role in the formation of amyloid plaques.
  3. Insulin is also involved in the phosphorylation of tau, which leads to neurofibrillary tangles.
  4. Insulin resistance in the body can lead to type 2 diabetes and insulin resistance in the brain can lead to the plaques and tangles of Alzheimer’s disease.

Lower your risk of diabetes and dementia
Dr Budson is a doctor, but he advises that if you want to check out how you can lower your risk of type 2 diabetes – and your risk of dementia, you need to speak with your doctor today to find out if the style changes. following life would suit you. .

He reiterates that whether you are diagnosed with diabetes or prediabetes, if your doctor gives you the green light, you may find that these lifestyle changes will provide you with a host of benefits by helping lower your risk of developing. dementia.

  1. Get aerobic exercise for at least 30 minutes a day, five days a week.
  2. Eat a menu of Mediterranean style dishes.
  3. Maintain a healthy body weight.
  4. Treat high blood pressure.
  5. Treat high cholesterol.
  6. Do not smoke.

RESULTS : Unlike the West, in India most older people live with their families and most dementia patients are cared for by their families. With the increase of the elderly population and the reduction of the common family system in our country, dementia poses a great challenge. While changes in lifestyle can prevent or delay the onset of dementia (mainly caused by diabetes), they can improve the quality of life not only for the patient, but for the person’s entire family.

Disclaimer: The tips and suggestions mentioned in the article are for general information purposes only and should not be construed as professional medical advice. Always consult your doctor or dietitian before starting a fitness program or making any changes to your diet.