Boron is an essential mineral for optimal health and fitness. This nutrient has pleiotropic effects, which can have multiple beneficial effects on the body.
NEW YORK, NEW YORK, USA, Aug. 29, 2022 /EINPresswire.com/ — Boron may also aid in the modulation of various bodily systems. Recently, scientists have discovered boron polymorphisms linked to disease in various species, highlighting the growing importance of this mineral for human health.
Occurrence and Sources of Boron
Boron is a metalloid element that exists in small amounts in the environment. It is an essential micronutrient for plants but can be toxic to animals at high concentrations.
Boron occurs naturally in rocks, soil, water and air – weathering of rocks and volcanic activity release boron into the environment. Plants absorb boron from the soil and concentrate it in their tissues. Animals absorb boron from plants or other animals that have eaten plants.
Most people are exposed to low levels of boron in food, air, and water. Higher exposure levels may occur near certain industrial facilities that release boron to air or use it in manufacturing processes.
How Boron Affects Human Health
Boron is a mineral necessary for human health because it participates in hydroxylation reactions, which are vital for the synthesis and metabolism of various substances. Boron is an effective arthritis treatment that improves bone development in 95% of cases by improving calcium absorption in bones, joints and cartilage. It also impacts many hormones, including testosterone and estrogen. Boron neutron capture agents may help in the treatment of cancer. Boron formulations can also be used to attack breast cancer cells in vitro.
Boron is thought to affect blood clotting. It alleviates the symptoms of congestive heart failure. Boron reduces the accumulation of lipids and allows the elimination of cholesterol in various ways, reducing the risk of developing conditions such as blood clots and atherosclerosis and protecting the body against heart attacks and strokes.
Borates like boron have various inhibitory actions on enzymes, making them useful for cancer, wound healing, and disease control. They also reduce genotoxicity. Additionally, boric acid enhanced the function of acetylcholinesterase, which is suppressed by pesticides and protects the human body from oxidative stress caused by CCL 4 and other agents.
Boron stimulates bone growth
Boron is important for bone development as it contributes to metabolism, bone regeneration, bone formation and mineralization. It is also known to influence various metabolic activities in bone, such as its interaction with magnesium, vitamin D and calcium, which are essential for bone metabolism. This synergistic relationship with Ca and Mg homeostasis contributes to its role in bone strength for human health and well-being.
Aging can lead to bone weakness in porous bones, and boron can help overcome this aggravation by ensuring that calcium and magnesium levels are working properly. Boron stimulates osteoblastic cell activity via the influx of calcium, i.e. calcium fructoborate, which significantly decreases serum C-reactive protein levels, indicating that this unique plant mineral borate preparation improves bone energy and strength by reducing inflammation associated with loss of bone mineral density.
Additionally, boron has been shown to facilitate bone metabolism with proliferation, cell survival, osteoblast protein mRNA expression, and mineralization.
Boron for embryonic development
Pregnant women should pay special attention to their diet, since the fetus is completely dependent on maternal nutrition. This includes trace elements, which are essential for the normal development of the fetus. If these nutrients are not properly passed to the fetus, it can lead to mineral deficiencies that can lead to fetal dysplasia and other irregularities.
Also, newborns who do not receive adequate maternal nutrition during gestation or pregnancy are more likely to be deficient in minerals and other nutrients during childhood.
Many researchers have studied the role of boron nutrition in animal and human health. Nielsen’s “stress model” is a widely used hypothesis that suggests that the lack of one or more nutrients in the diet can lead to negative health outcomes and the effects of boron supplementation on low-fat diets. copper or magnesium levels in the body. In these situations, boron altered the biochemistry of various nutritional indicators, including hemoglobin, blood sugar, platelets, and hormone levels.
Boron is good for brain activity
Boron is an essential element for brain function, and its deficiency causes adverse effects on the central nervous system. Studies of human brain activity have revealed that a lack of boron in the diet leads to reduced electrical activity in the brain.
Boron supplementation (3 mg/day) in participants following a diet containing approximately 0.25 mg boron/2000 kcal for approximately 63 days alters the electroencephalogram, with a tendency to action at lower frequencies and greater interaction at higher frequencies of the dominant frequency spectrum.
Meanwhile, supplemental boron has been associated with better psychomotor skills, less drowsiness, mental clarity, improved short-term memory, and increased attention in older men and women.
Boron and its role in wound healing
Boron is known for its healing properties, as a 3% solution of boric acid has been reported to heal deep wounds. Boric water (pharmacopoeia) was previously known for its antimicrobial properties. Today, borates are used in very low concentrations to treat various wounds and improve human health.
The mode of action of boron in wound healing is associated with the synthesis of proteins, collagen and proteoglycans. Boron also controls the growth of the extracellular matrix, which aids in wound healing by stimulating the expression of proteins, collagen and proteoglycans. It also promotes the release and synthesis of tumor necrosis factor.
Boron for hormone metabolism
Boron is a nutrient that improves steroid hormone metabolism, particularly sex hormone metabolism, by increasing testosterone levels in men and estrogen levels in postmenopausal women. It has also been found that intensive training for two months could reduce testosterone production in non-professional bodybuilders.
Nevertheless, boron supplementation effectively regulates this hormonal level for optimal human health. It can also increase estrogen levels in postmenopausal women, allowing them to regain their sexual energy a few days after starting treatment. Boron can reduce the need for pharmaceutical solutions or hormone replacement therapy by increasing the natural level of sex hormones in the body.
Boron may also ease menopausal symptoms such as night sweats and hot flashes, confirming adequate mineral levels. Postmenopausal women frequently suffer from hormonal imbalances affecting the most important processes in the body.
Boron is key to a healthy immune response
Boron influences immune cell populations in response to other dietary factors, such as fatty acids. A 12-week study in healthy young men found that n-3 polyunsaturated fatty acid (PUFA-3) supplementation at a dose of 6 g/day decreased the number of white blood cells, primarily decreasing the number of granulocytes. As a result, the proportion of lymphocytes in white blood cells increased.
However, the mechanisms underlying boron’s anti-inflammatory or immune response capabilities have been attributed to several factors, including suppression of serine proteases, leukotriene synthesis, decreased oxidative stress, modulation of activity T lymphocytes and the regulation of antibody concentrations.
Boron may help fight cancer
Boric acid positively influences prostate cancer cells to maintain good human health. These anti-carcinogenic properties could be linked to their effects on NAD and calcium channels.
NAD is required for cellular cholesterol and fat production. The movement of Ca++ into and out of cells is also important for cell survival. When NAD/NADP development is interrupted, cell function suffers. Boric acid concentration has been found to affect NAD production and Ca++ secretion in cancer cells.
Borates are beneficial for cancer treatment by inhibiting cell growth and flattening prostate cancer cells. They reduce cytochemicals, MAPKs, and AE cyclins, resulting in cells with weaker adhesion, F-actin changes, invasive activity, and migration. Boric acid inhibits tumor cell proliferation in LNCaP and DU-145 cell lines and strongly inhibits tumor growth.
A note on toxicity
The primary human health concern associated with exposure to boron is its potential toxicity. Boron causes skin and eye irritation and respiratory effects if inhaled. Ingestion of large amounts of boron can lead to gastrointestinal disturbances, diarrhea and vomiting. Severe conditions can lead to coma or death. Long-term exposure to low levels of boron can lead to kidney damage.
Despite these potential human health effects, there is currently no evidence that exposure to boron levels commonly found in the environment poses a significant health risk.