Home Cellular science Indian scientists study long-term memory of covid-19 vaccination

Indian scientists study long-term memory of covid-19 vaccination


NEW DELHI : Scientists at the Department of Biotechnology (DBT) are studying the long-term memory of covid-19 vaccination in the human body, including the quality and durability of bites.

The research results will impact future vaccine dosing strategies, including for booster doses.

DBT Secretary Rajesh Gokhale said: “Given the widespread vaccination against covid-19 in the country, the study aims to understand the long-term immune responses of the population. Memory studies are relatively complex studies unlike antibody studies and involve cell therapies that require isolating cells, tracking cells, antigens, and then examining the cells, which is called the cellular response. These require standardization of assays, virus isolation, and examination of the infected and uninfected population. Response of one vaccine versus another vaccine.”

This study should also help the government design public health responses to future pandemics and viruses.

“We need to understand the long-term importance of our vaccination. Before the covid-19 vaccination, all the vaccines we took were studied for 4-5 years and then decided. Therefore, we need to do a good study about it to know the long term memory of vaccination in our body. It is necessary to know if there is superinfection; So how does it work ? How good is the memory and how good is the quality and durability? We are taking vaccination data for this and several labs in the Department of Biotechnology are conducting the study,” Gokhale said.

India’s covid-19 vaccination coverage has exceeded 1.97 billion doses.

However, only 7% of 18-60 year olds and 40% of over 60s have received the booster shot so far.

“Never before in this world has such a large amount of vaccine been given in such a short time. So it’s a fantastic way to study how to assess the immune response occurring in the population. And this study can provide data for several other viruses and vaccination strategies. This has very big implications in terms of understanding vaccination than what is being done right now,” Gokhale said.

Speaking about the recent increase in covid-19 cases, the scientist said: “At the moment no new variants are coming and small recombinant variants are also very few. All variants have a very similar pattern.”

India recorded 11,739 new cases and 25 deaths in the past 24 hours.

The number of active cases soared to more than 92,576, bringing the total number of cases to 43 million and deaths to 524,999, the government said. Unofficial estimates are much higher.

Asked about the reasons for the increase, the DBT chief said: “These are sporadic events and they keep happening. Because then only endemicity will occur. Endemicity will occur when you have a very robust T-cell response in the nasal airways.”

“The nasal airway response is slowly growing in our country and continues to do so. He will eventually take the flu pattern. People should continue to wear masks and follow covid-19 appropriate behavior.”

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